This high magnification image shows trabeculae of new bone (primary spongiosa), composed of woven bone. The pale-colored, cell free matrix is hyaline cartilage matrix, which has been covered with woven bone matrix, characterized by the absence of lamellar substructure. Osteocytes are seen in the bone matrix within lacunae. Osteoblasts form a single epithelial-like layer on the surface of some of the trabeculae. In the center of the image, a thin layer of light-staining osteoid can be seen between a group of osteoblasts and the dark-staining calcified bone matrix. Two large osteoclasts can be seen at the right margin of the image, located at the ends of trabeculae. The spaces between the bone trabeculae are occupied by developing bone marrow cells.
Stain = H&E
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| Copyright by: Paul B. Bell, Jr. & Barbara Safiejko-Mroczka |
The University of Oklahoma